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Dr Clarence Maikuri Mang'era

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Staff Information
PERSONAL DETAILS
Designation
LECTURER
Corporate Email
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Job Category
Teaching
Division / Faculty
Faculty of Science
Directorate / Dept
DEPT. OF BIOCHEMISTRY & MOLECULAR BIO
Section
Academic
SUMMARY

Clarence Mang’era, PhD is a Scientist in where he researches mosquito and Tsetse ecology and physiology. His graduate research focused on the effects of bioactive phytochemical compounds on selected structural and hormonal components of mosquito larvae. Previously, he studied mosquito developmental changes in at ICIPE. Clarence also researched surveillance of resistance status of malaria drug interventions in Kenya while he was attached to the Kenya Medical Research Institute - , Nairobi (Kenya). He continues to investigate the potential of various chemical compounds in controlling major disease vectors in sub-Saharan Arica.

Clarence is a lecturer at Egerton University, Department of Biochemistry and Molecular Biology where he teaches Biochemistry, Molecular Biology, and Entomology. He also reviews manuscripts for journals such as PLoS Neglected Tropical Diseases – and Journal of Insect Science – . Clarence is an Executive Council Member of the representing Kenya (Biochemical Society of Kenya). As an early career scientist, Clarence is actively seeking postdoctoral opportunities that will build local research capacity in Kenya and establish long-term international collaborations in vector-borne disease control. 

ORCID
Researchgate
Google Scholar
ACADEMIC QUALIFICATIONS
  1. Ph.D. Biochemistry - Kenyatta University, Kenya
  2. MSc Biochemistry - Egerton University, Kenya
  3. BSc Biomedical Science and Technology - Egerton University, Kenya

 

FIELDS OF SPECIALIZATION
  • Molecular Entomology (Disease vector control)
  • Molecular Parasitology
  • Integrated vector management (IVM) in mosquito control
  • Bioinformatics (NGS data processing, Genome annotation)
  • Phytochemistry
PROFESSIONAL QUALIFICATIONS

Genome annotation (VectorBase)

Reviewer for Scientific Journals (Publons):

  • International journal of tropical insect science - Springer Nature
  • Journal of Herbal Medicine - Elsevier
  • Journal of Insect Science - Oxford University Press
  • PLoS Neglected Tropical Diseases - PLOS

Laboratory Biosafety and Biosecurity

WORK EXPERIENCE
  • July 2021 - Present Lecturer, Department of Biochemistry and Molecular Biology, Egerton University
  • July 2013 - July 2021 Assistant Lecturer, Department of Biochemistry and Molecular Biology, Egerton University
  • March 2014 – Aug 2017 PhD internship (DRIP) - The International Centre of Insect Physiology and Ecology (icipe)
  • Sep 2011- Feb 2013 Graduate Assistant – Egerton University
  • Sep 2010 – May 2013 Graduate Assistant – Technical University of Kenya
  • May 2009 – Aug 2010 Student Research Assistant – Kenya Medical Research Institute

 

KEY PROJECTS
  • June 2013 – Feb  2016 : Toxicity of Curry tree Phytochemical(s) to Anopheles gambiae Malaria Vector Donor: Grand Challenges Canada; Total Funding: CAD 100,000 for 18 months. Partners: ICIPE - Kenya, Egerton University-Kenya, Kenyatta University - Kenya, (PI-Kenya: Mr. Mang’era Clarence)
RESEARCH INTERESTS

Biology of disease vectors (Mosquito, Tsetse)

Neglected tropical diseases

Computational and cell biology

Phytochemistry

 

LIST OF PUBLICATIONS

  1. 1.      Ogolla KO, Onyango T, Bwana BK, Otiende MY, Mang’era CM, Ochieng B, Omolo MO, Mugambi JM, Hassanali A, Omondi P and Mireji PO (2023) Bloodmeal host identities among sympatric Glossina austeni and Glossina pallidipes tsetse flies in Shimba Hills National Reserve, Kwale, Kenya. Front. Trop. Dis 4:1145993. doi:10.3389/fitd.2023.1145993

    2.      Mireji PO, Mang’era CM, Bwana BK and Hassanali A (2022) Perspectives on Odor-Based Control of Tsetse Flies in Africa. Front. Physiol. 13:831618. doi: 10.3389/fphys.2022.831618

    3.      Mutuku CN; Bateta R;  Rono MK;  Njunge JM;  Awuoche EO;  Ndung'u K; Mang'era CM;  Akoth MO;  Adung'a VO;  Ondigo BN;  Mireji PO. Physiological and proteomic profiles of Trypanosoma brucei rhodesiense parasite isolated from suramin responsive and non-responsive HAT patients in Busoga, Uganda. Int J Parasitol Drugs Drug Resist. 2021;15:57-67;

    4.      Mang'era, CM.;  Khamis, FM.;  Awuoche, EO.;  Hassanali, A;  Ombura, FLO;  Mireji, PO. Transcriptomic response of Anopheles gambiae sensu stricto mosquito larvae to Curry tree (Murraya koenigii) phytochemicals. Parasit Vectors. 2021; Jan 2;14(1):1.

    5.      Kabaka JM, Wachira BM, Mang’era CM, Rono MK, Hassanali A, Okoth SO, et al. Expansions of chemosensory gene orthologs among selected tsetse fly species and their expressions in glossina morsitans morsitans tsetse fly. PLoS Negl Trop Dis. 2020;14:1–23.  

    6.      Mang’era CM, Hassanali A, Khamis FM, Rono MK, Lwande W, Mbogo C, Mireji PO. 2018. Growth-disrupting Murraya koenigii leaf extracts on Anopheles gambiae larvae and identification of associated candidate bioactive constituents. Acta Trop. 190:304–11.

    7.      Mang’era, C.M., Mbai F.N., Omedo I.A., Omar S.A., 2012. Changes in genotypes of Plasmodium falciparum human malaria parasite following withdrawal of chloroquine in Tiwi, Kenya. Acta Trop. 123, 202-207.

    8.      Shaviya, N., Mang’era, C.M., Makokha, F.W., Kimani, F.T., Ongus, J.R. 2012 Expansion of the wildtype pfcrt 76K allele in Plasmodium falciparum populations in Mbita, Kenya. African Journal of Health Sciences 22, 176-187.

    9.      Shaviya, N., Zablon, J.O., Mang’era, C.M., Makokha, F.W., Wamalwa, R.W., Sowayi, G.A. 2014. Genotyping for point mutations in selected codons of pfcrt and pfmdr-1 genes of Plasmodium falciparum among patients with uncomplicated malaria in Mbita district Kenya. Journal of Natural Sciences Research 4, 114-123.

CONFERENCES & INVITED PRESENTATIONS

Mang'era C.M. (2021, July 16) Induction of Molecular and Physiological Responses in Malaria Vectors to Curry Tree Leaf Phytochemicals. Seminar presented at Postgraduates conference, Kenyatta University.

TEACHING AREAS
  • Biomedical Sciences and Technology
  • Biochemistry
  • Research Methods
OTHER SOCIETIES
  1. Member - American Society of Tropical Medicine and Hygiene (ASMTH)
  2. Member - The American Committee of Medical Entomology (ACME)
  3. Council Member - Federation of African Societies of Biochemistry and Molecular Biology (FASBMB) 
  4. Organizing committee member - Biochemistry and Biotechnology Professionals Society of Kenya (BBPSK) 
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